hurg-Strauss syndrome is a kind of rare systemic vasculitis characterized by peripheral
eosinophilia, bronchial asthma and relatively specific pathological findings such as necrotizing
vasculitis, eosinophilic infiltration of tissue and/or extravascular granuloma. Clinically multiple
organs/systems can be involved with various manifestations of disease of lung, heart, skin,
musculoskeletal system, nervous system and gastrointesinal/hepatobiliary tract. Gastriontestinal
symtoms were frequently accompanied, but usually mild and easily controllable so that special
study for evaluation of the symptoms hardly seemed to be needed.We experienced a case of
Churg-Strauss syndrome presenting as esophageal ulcers, acute acalculous cholecystitis and
treatment-resistant ischemic colitis in a 24-year-old male patient with acute upper abdominal
pain and watery, often bloody diarrhea. He also showed peripheral eosinophilia, bronchial
asthma, mononeuritis multiplex, skin rash and arthritis.The patient received high dose
corticosteriod, cyclophosphamide and exchange plasmapheresis with resolution of almost all
symtoms. But symptoms of ischemic colitis such as abdominal pain and diarrhea are not
completely improved in spite of intensive therapy.
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